Bioss Inc.'s SHANK 1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen. The SHANK 1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated was generated using SHANK1 as the antigen and it reacts with Human.
Description
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction